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Solution Structure of a Cis-Opened (10 R )- N 6 -Deoxyadenosine Adduct of (9 S ,10 R )-9,10-Epoxy-7,8,9,10-tetrahydrobenzo[ a ]pyrene in a DNA Duplex †,‡

✍ Scribed by Volk, David E.; Thiviyanathan, Varatharasa; Rice, Jeffrey S.; Luxon, Bruce A.; Shah, Jamshed H.; Yagi, Haruhiko; Sayer, Jane M.; Yeh, Herman J. C.; Jerina, Donald M.; Gorenstein, David G.


Book ID
127025444
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
374 KB
Volume
42
Category
Article
ISSN
0006-2960

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The reaction of (±)-7α, 8β-dihydroxy-9β,
✍ M. R. Osborne; P. Brookes; F. A. Beland; R. G. Harvey 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 539 KB

## Abstract The reaction of (±)‐7α,8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo(__a__)pyrene (BP diol epoxide) with DNA, followed by enzymatic hydrolysis and LH 20 Sephadex column chromatography, yielded products containing a purine deoxyribonucleoside linked to a 7,8,9,10‐tetrahydrobenzo(__a