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Solution structure and biological activity of recombinant salmon calcitonin S-sulfonated analog

✍ Scribed by Yuefeng Wang; Hong Dou; Chunyang Cao; Naixia Zhang; Jingbiao Ma; Jifang Mao; Houming Wu

Book ID
117054103
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
422 KB
Volume
306
Category
Article
ISSN
0006-291X

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## Abstract Gramicidin S (GS) is a cyclo‐decapeptide antibiotic isolated from __Bacillus brevis__. The structural studies have shown that GS forms a two‐stranded antiparallel β‐sheet imposed by two II′ β‐turns. Despite its wide Gram+ and Gram− antimicrobial spectrum, GS is useless in therapy becaus