Solution Phase Synthesis of Amide-Linked N-Acetyl Neuraminic Acid, α-Amino Acid, and Sugar Amino Acid Conjugates. -It is shown that NeuAc can be efficiently conjugated to naturally occurring α-amino acids and subsequently to sugar amino acids yielding diverse compounds with potential biological act
Solution Phase Synthesis of Amide-Linked N -Acetyl Neuraminic Acid, α-Amino Acid, and Sugar Amino Acid Conjugates 1
✍ Scribed by Ramamoorthy, P. S.; Gervay, Jacquelyn
- Book ID
- 126419202
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 198 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
Carboxy-protected amino derivatives and amino-protected carboxy derivatives of three different C-2 analogs as well as a 2,3-dehydro NeuAc were prepared. These monomers were coupled in solution using BOP activation of the carboxy terminus to form (l~5)-amide linked dimers of sialyl amino acid derivat
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