Solution-phase parallel synthesis of benzoxazines using a polymer-supported carbodiimide

✍ Scribed by Brad O. Buckman; Michael M. Morrissey; Raju Mohan

• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 139 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00012-4

✦ Synopsis

A diverse library of 2-aminobenzoxazines 3 has been synthesized using a two step approach. Addition of anthnmilie acids to isoeyanates affords ureas 2 that can be eyelized by polymer-supported EDC to give 2-aminobenzoxazines 3.