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Expeditious synthesis of mosher amides using a solid supported carbodiimide

✍ Scribed by Maciej Adamczyk; Jeffrey R. Fishpaugh

Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
132 KB
Volume
37
Category
Article
ISSN
0040-4039

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✍ Brad O. Buckman; Michael M. Morrissey; Raju Mohan πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 139 KB

A diverse library of 2-aminobenzoxazines 3 has been synthesized using a two step approach. Addition of anthnmilie acids to isoeyanates affords ureas 2 that can be eyelized by polymer-supported EDC to give 2-aminobenzoxazines 3.