Solution phase parallel synthesis of 1,2-phenethyldiamines

✍ Scribed by Christopher T Lowden; Jose S Mendoza

• Book ID: 104232354
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 140 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02313-9

✦ Synopsis

A versatile solution phase synthesis for the preparation of 1,2-phenethyldiamines has been developed for the purpose of producing lead generation libraries. A facile strategy for the parallel purification of products provides high purity products suitable for SAR evaluation in high-throughput screening assays.