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Solute-solvent interactions and acid-base dissociation in mixed solvent systems

✍ Scribed by Roger G. Bates


Publisher
Elsevier Science
Year
1971
Weight
944 KB
Volume
29
Category
Article
ISSN
0022-0728

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An equation is derived relating total and preferential interactions of solvent components with macromolecules in a three-component system. Application of this equation to literature data shows that binding of non-polar solvents to proteins parallels the unfolding of the latter. This observation is d