Urokinase plasminogen activator (uPA) is a serine protease causally involved in cancer invasion and metastasis. Consistent with its role in cancer spread, uPA has been shown to be a prognostic marker in a variety of malignancies, especially breast cancer. Approximately 20 different groups have shown
Soluble urokinase plasminogen activator receptor as a prognostic marker in men participating in prostate cancer screening
✍ Scribed by A. Kjellman; O. Akre; O. Gustafsson; G. Høyer-Hansen; H. Lilja; U. Norming; T. Piironen; M. Törnblom
- Book ID
- 108863799
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 167 KB
- Volume
- 269
- Category
- Article
- ISSN
- 0954-6820
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## Urokinase -type plasminogen activator (u-PA) is thought to be implicated in cancer invasion and metastasis. The aim of this study was to determine whether the u-PA content of cancer tissue is a prognostic factor in bladder cancer. Tissue samples from 46 patients with bladder cancer were assesse
## Abstract Circulating soluble urokinase plasminogen activator receptor (suPAR) reflects the immune and pro‐inflammatory status of the HIV‐infected patient. Highly active antiretroviral therapy (HAART) suppresses suPAR. Independent of the immune response to HAART, suPAR remains elevated in some HI