Soluble HLA-G Molecules Induce Apoptosis in Natural Killer Cells
β Scribed by Amy Lindaman; Amy Dowden; Nicholas Zavazava
- Book ID
- 111269970
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 282 KB
- Volume
- 56
- Category
- Article
- ISSN
- 8755-8920
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There is convincing evidence that soluble HLA-A,-B,-C (sHLA-A,-B,-C) and soluble HLA-G (sHLA-G) antigens can induce apoptosis in CD8(+) activated T cells although there is scanty and conflicting information about the mechanism(s) by which sHLA-A,-B,-C antigens and sHLA-G antigens induce apoptosis. I
The high mortality of colon cancer is to a large extent caused by the frequent occurrence of liver metastasis. This is remarkable, because the liver harbors two distinct cell populations that can eliminate invading cancer cells, namely hepatic natural killer (NK) cells and Kupffer cells. These hepat