Solubilization of membrane-associated tumour-specific antigens by β-glucosidase
✍ Scribed by R.W Baldwin; J.G Bowen; M.R Price
- Book ID
- 115722454
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 713 KB
- Volume
- 367
- Category
- Article
- ISSN
- 0005-2736
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📜 SIMILAR VOLUMES
10' cells per ml antiserum. Membrane equivalent loB cells per ml antiserum.
## Abstract It has previously been shown that the tumourspecific antigen of the chemically‐induced rat hepatoma D23 has determinants recognised by alloantisera raised against normal syngeneic liver and spleen. However, no reactions were observed with alloantisera raised against syngeneic erythrocyt
We describe a novel version of antibody-directed enzyme prodrug therapy (ADEPT), with the use of amygdalin as prodrug. Amygdalin is a naturally occurring cyanogenic glycoside, which can be cleaved by sweet almond -glucosidase to yield free cyanide. If amygdalin could be activated specifically at th