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Solid state interaction of bromazepam with polyvinylpyrrolidone in the presence of moisture

✍ Scribed by Fassihi, A.R.; Persicaner, P.H.R.

Book ID
123437484
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
607 KB
Volume
37
Category
Article
ISSN
0378-5173

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During stability studies at high temperature (70 degrees C) and low relative humidity ( approximately 0%), the recovery of an asparagine containing hexapeptide (VYPNGA) and its known deamidation products from solid polyvinylpyrrolidone (PVP) matrices was incomplete. To determine the causes of this m