Solid State Characterization of Pharmaceuticals

✍ Scribed by Richard L. Story

• Publisher: Blackwell Pub Professional
• Year: 2011
• Tongue: English
• Leaves: 517
• Category: Library

✦ Synopsis

The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties.This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. The following topics are included:    Physical properties and processesThermodynamicsIntellectual  guidanceX-ray diffractionSpectroscopy MicroscopyParticle sizingMechanical propertiesVapour sorptionThermal analysis & CalorimetryPolymorph predictionForm selection

✦ Table of Contents

fmatter.pdf......Page 1
ch1.pdf......Page 19
ch2.pdf......Page 53
ch3.pdf......Page 89
ch4.pdf......Page 153
ch5.pdf......Page 205
ch6.pdf......Page 225
ch7.pdf......Page 250
ch8.pdf......Page 261
ch9.pdf......Page 302
ch10.pdf......Page 371
ch11.pdf......Page 401
ch12.pdf......Page 440
ch13.pdf......Page 464
ch14.pdf......Page 485
index.pdf......Page 504