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Solid-phase synthesis of γ-lactams, γ-lactones and cyclobutane derivatives from common resin-bound intermediates

✍ Scribed by Richard C.D Brown; John Keily; Rehana Karim

Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 171 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)00359-2

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✦ Synopsis

Resin-bound cyclobutanone iminium salts, prepared on the solid-phase using the [2+2]-keteneiminium olefin cycloaddition reaction, have been transformed into a number of distinct structural classes including γ-lactams, γ-lactones, cyclobutylamines and cyclobutanols.

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