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Solid Phase Synthesis of Tertiary Amines on Amide REM Resins: Grignard and Metal Hydride Compatible Resins

โœ Scribed by Plater, M. John; Murdoch, Alison M.; Morphy, J. Richard; Rankovic, Zoran; Rees, David C.


Book ID
126068129
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
101 KB
Volume
2
Category
Article
ISSN
1520-4766

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Methods for the synthesis of chloromethyl and bromomethyl equivalents of Wang's resin are described. To explore the utility of this acid cleavable resin, amines were immobilized through the nitrogen atom, further functionalized, and then cleaved under acid conditions.