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Use of halomethyl resins to immobilize amines: An efficient method for synthesis of sulfonamides and amides on a solid support

✍ Scribed by B. Raju; Timothy P. Kogan


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
295 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis


Methods for the synthesis of chloromethyl and bromomethyl equivalents of Wang's resin are described. To explore the utility of this acid cleavable resin, amines were immobilized through the nitrogen atom, further functionalized, and then cleaved under acid conditions.