Solid Phase Synthesis of 17Ξ±-E/Z-(X-Phen
β
Choon Young Lee; Robert N Hanson
π
Article
π
2000
π
Elsevier Science
π
French
β 131 KB
As a continuation of our program to develop probes for the hormone binding domain (HBD) of the estrogen receptor (ER), we designed a series of novel 17a-E/Z-(X-phenyl)-vinyl estradiols. Based upon our experience with solution chemistry we applied solid phase synthesis using carboxylated resins to sy