An efficient method for the solid-phase synthesis of substituted guanidines is presented. A variety of alcohols react with resin-bound N,N'-bis(t-butoxycarbonyl)thiopseudourea under Mitsunobu conditions to give the corresponding alkylated thiopseudoureas. The guanidines are liberated from the resin
✦ LIBER ✦
Solid-phase synthesis of N-acyl-N′-carbamoylguanidines
✍ Scribed by Peishan Lin; A. Ganesan
- Book ID
- 108387214
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 202 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Solid-phase synthesis of N,N′ substitute
✍
Dharmpal S. Dodd; Owen B. Wallace
📂
Article
📅
1998
🏛
Elsevier Science
🌐
French
⚖ 201 KB
A novel solid-phase synthesis of di- and
✍
Jacob Ravn; Michael Ankersen; Mikael Begtrup; Jesper F. Lau
📂
Article
📅
2003
🏛
Elsevier Science
🌐
French
⚖ 376 KB
A novel, mild method for the synthesis of di-and trisubstituted N-acyl ureas on solid support is described. Addition of carboxylic acids to a resin-bound carbimidoyl chloride gave, initially, an O-acyl isourea which subsequently rearranged to the corresponding N-acyl urea. Trisubstituted N-acyl urea
Solid phase synthesis of N-arylazoindole
✍
Susanta Khound; Pranab J Das
📂
Article
📅
1997
🏛
Elsevier Science
🌐
French
⚖ 237 KB
Solid-phase synthesis of acyl biarylsulf
✍
Yusheng Xiong; John Klopp; Kevin T Chapman
📂
Article
📅
2001
🏛
Elsevier Science
🌐
French
⚖ 136 KB
N-Linked solid phase peptide synthesis
✍
Roger Le´ger; Rose Yen; Miles W. She; Ving J. Lee; Scott J. Hecker
📂
Article
📅
1998
🏛
Elsevier Science
🌐
French
⚖ 218 KB
Efficient Solution Phase Synthesis of 2-
✍
Punit P. Seth; Dale E. Robinson; Elizabeth A. Jefferson; Eric E. Swayze
📂
Article
📅
2010
🏛
John Wiley and Sons
⚖ 29 KB