✦ LIBER ✦

Solid-phase synthesis of isoindolines via a rhodium-catalyzed [2+2+2] cycloaddition

✍ Scribed by Qun Sun; Xiaoming Zhou; Khondaker Islam; Donald J Kyle

Book ID: 104231412
Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 95 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)01356-9

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✦ Synopsis

An efficient solid-phase synthesis of isoindolines is reported. The key reaction step is a rhodium-catalyzed [2+2+2] cycloaddition of alkynes to give isoindolines in good yield.

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