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Solid-phase synthesis of asymmetric cyanine dyes

โœ Scribed by Jennie Isacsson; Gunnar Westman

Book ID
104230436
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
103 KB
Volume
42
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

An efficient solid-phase synthesis of asymmetric cyanine dyes is described. Combinatorial synthesis and spectroscopic analysis of four dyes was carried out. The yields are quantitative after 20 h, but the reaction can be halted earlier, since it is shown that the starting material does not disturb the fluorescence measurements in these binding studies.

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