✦ LIBER ✦

Solid-phase synthesis of 4-aryl-1,4-dihydropyridines via the Hantzsch three component condensation

✍ Scribed by J.Guy Breitenbucher; Gina Figliozzi

Book ID: 104210394
Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 159 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)00660-2

No coin nor oath required. For personal study only.

✦ Synopsis

We report the synthesis of 1,4-dihydropyridines on solid support utilizing the Hantzsch condensation. Unwanted reactive impurities were removed from the desired products, by selective cleavage from solid support. The synthesis of a 272 compound library is reported using the methods described.

📜 SIMILAR VOLUMES

Synthesis of polysubstituted 1,4-dihydro

Synthesis of polysubstituted 1,4-dihydropyridines via three-component reaction

✍ Saeed Balalaie; Leila Baoosi; Fatemeh Tahoori; Frank Rominger; Hamid Reza Bijanz 📂 Article 📅 2013 🏛 Elsevier Science 🌐 French ⚖ 526 KB

ChemInform Abstract: An Efficient Synthe

ChemInform Abstract: An Efficient Synthesis of 4-Aryl-1,4-dihydropyridines via VB1-Catalyzed Hantzsch Reaction.

✍ Chuangang Fan; Mingzhi Song 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 30 KB

ChemInform Abstract: One-Pot Synthesis o

ChemInform Abstract: One-Pot Synthesis of 1,4-Dihydropyridines via a Phenylboronic Acid Catalyzed Hantzsch Three-Component Reaction.

✍ Abdelmadjid Debache; Raouf Boulcina; Ali Belfaitah; Salah Rhouati; Bertrand Carb 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 19 KB 👁 2 views

Studies on Dihydropyridines. I. The Prep

Studies on Dihydropyridines. I. The Preparation of Unsymmetrical 4-Aryl-1,4-dihydropyridines by the Hantzsch-Beyer Synthesis 1

✍ Berson, Jerome A.; Brown, Earlene 📂 Article 📅 1955 🏛 American Chemical Society 🌐 English ⚖ 489 KB

An efficient one-step synthesis of 1,4-d

An efficient one-step synthesis of 1,4-dihydropyridines via a triphenylphosphine-catalyzed three-component Hantzsch reaction under mild conditions

✍ Abdelmadjid Debache; Wassima Ghalem; Raouf Boulcina; Ali Belfaitah; Salah Rhouat 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 293 KB

a b s t r a c t An efficient one-step synthesis of 1,4-dihydropyridines in good to excellent yields via the triphenylphosphine-catalyzed Hantzsch three-component reaction of an aromatic aldehyde, ethyl acetoacetate and ammonium acetate is described.

ChemInform Abstract: An Efficient One-St

ChemInform Abstract: An Efficient One-Step Synthesis of 1,4-Dihydropyridines via a Triphenylphosphine-Catalyzed Three-Component Hantzsch Reaction under Mild Conditions.

✍ Abdelmadjid Debache; Wassima Ghalem; Raouf Boulcina; Ali Belfaitah; Salah Rhouat 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views