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Solid-Phase Synthesis of 1,4-Benzodiazepine-2,5-diones. Library Preparation and Demonstration of Synthesis Generality

โœ Scribed by Boojamra, Constantine G.; Burow, Kristina M.; Thompson, Lorin A.; Ellman, Jonathan A.


Book ID
120645743
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
452 KB
Volume
62
Category
Article
ISSN
0022-3263

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## Abstract An efficient solidโ€phase synthetic method for 2,3,4,5โ€Tetrahydroโ€1,4โ€benzodiazepinโ€2,5โ€diones, having amine derivatives on the benzene ring, was developed. This method has been successfully applied to the synthesis of several spatially separated drugโ€like and informationโ€rich smallโ€mole