Solid-Phase Synthesis of 1-Substituted Tetrahydroisoquinoline Derivatives Employing BOC-Protected Tetrahydroisoquinoline Carboxylic Acids
β Scribed by Bunin, Barry A.; Dener, Jeffrey M.; Kelly, Daphne E.; Paras, Nick A.; Tario, James D.; Tushup, Steven P.
- Book ID
- 118021432
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 157 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1520-4766
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A new and general synthetic methodology for the preparation of functionalized 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives by a cycloaddition strategy is described. The synthesis of various enyne building blocks 12, 13, 21, and 22 containing an Ξ±-amino acid moiety using Schiff base 8