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Solid-Phase Synthesis and Structural Characterization of Highly Substituted Hydroxyproline-Based 2,5-Diketopiperazines

✍ Scribed by Bianco, Alberto; Sonksen, Carsten P.; Roepstorff, Peter; Briand, Jean-Paul

Book ID
126072882
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
337 KB
Volume
65
Category
Article
ISSN
0022-3263

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## Abstract magnified image The synthesis of 3‐(hydroxyalkyl)‐__N,N__′‐disubstituted 2,5‐diketopiperazine derivatives ‐ compounds required for the bicyclomycin analogues preparation ‐ has been studied. The use of various oxo components in the Ugi multicomponent reaction (U‐MCR) has been evaluated.