Solid phase peptide synthesis using a cobalt(III) spacer between the resin and the peptide
β Scribed by Mensi, Nahla; Isied, Stephan S.
- Book ID
- 125990450
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 420 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
The use ofnucleophiles for the cleavage of an o-nitrobenzylester peptide-resin bond in order to afford peptide alkylesters and alkylamides has been studied. With this purpose, three short peptide sequences anchored to a Nbb-resin were used as models. Peptides were cleaved from the polymeric supports
## Synopsis Attachment of the side-chain carboxyl of the protected aspartic or glutamic acid ester to the resin support has been established for the solid-phase synthesis of the asparagine or glutamine peptide. After further elongation of the a-amino deprotected resin-bound peptide ester with prot