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Solid-phase peptide synthesis on a novel hydrogenolysable linker–resin combination

✍ Scribed by C. S. Pande; N. Gupta; A. Bhardwaj


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
404 KB
Volume
56
Category
Article
ISSN
0021-8995

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A new aminoethyl-polystyrene linker, stable at low concentrations of TFA, has been developed for the solid phase synthesis of peptide amides. The described linker is stable under conditions which remove Bu(t) protecting groups (30-50% TFA in DCM) and the desired product can be finally cleaved off th