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Solid-Phase Microextraction as a Powerful Tool in Photochemical Studies

✍ Scribed by Marta Lores; Lucia Sanchez-Prado; Maria Llompart; Carmen Garcia-Jares; Rafael Cela

Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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The decomposition of erythromycin A (EA) in aqueous solution was examined in the pH range 2-13 by means of combined solid-phase microextraction (SPME) and liquid chromatography/electrospray ionization tandem mass spectrometry. Degradation of EA, especially at lower pH values (pH 3), was very rapid a