Solid-phase immunoassay for the vitamin B12-binding protein transcobalamin II in human serum

Localization of the gene for the vitamin

Localization of the gene for the vitamin B12 binding protein, transcobalamin II, near the centromere on mouse chromosome 11, linked with the hemoglobin alpha-chain locus

✍ M. Fràter-Schröder; M. Prochazka; O. Haller; F. Arwert; H. J. Porck; L. C. Skow; 📂 Article 📅 1985 🏛 Springer 🌐 English ⚖ 684 KB

Somatic cell hybrids', recombinant inbred (RI) mouse strains, and backcross breeding experiments were used to locate the gene of transcobalamin H (Tcn-2), the vitamin BI 2 binding protein in mouse serum. TCN-2 was found to be a useful genetic marker in the somatic cell hybrids. Selected hybrid clone