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Solid-Phase and Solution-Phase Syntheses of Oligomeric Guanidines Bearing Peptide Side Chains

โœ Scribed by Zhang, Zhongsheng; Fan, Erkang

Book ID
125899020
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
448 KB
Volume
70
Category
Article
ISSN
0022-3263

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๐Ÿ“œ SIMILAR VOLUMES

Solid-phase synthesis of amino amides an
Solid-phase synthesis of amino amides and peptide amides with unnatural side chains
โœ William L Scott; Francisca Delgado; Karen Lobb; Richard S Pottorf; Martin J O'Do ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 86 KB

Unnatural amino amides and peptide amides can be synthesized, using solid-phase chemistry, from glycine attached directly (or through an intervening peptide sequence) to a Rink resin. The glycine is converted to an activated benzophenone imine derivative, followed by C-alkylation and hydrolysis. Thi