Sol–gel microextraction phases for sample preconcentration in chromatographic analysis

✍ Scribed by Scott S. Segro; MinhPhuong Tran; Sheshanka Kesani; Abdullah Alhendal; Erica B. Turner; Abdul Malik

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 637 KB
• Volume: 33
• Category: Article
• ISSN: 1615-9306
• DOI: 10.1002/jssc.201000316

✦ Synopsis

Abstract

Sol–gel technology provides a simple and reliable method for solid‐phase microextraction (SPME) fiber preparation through in situ creation of surface‐bonded organic–inorganic hybrid coatings characterized by enhanced thermal stability and solvent‐resistance properties that are important for the coupling of SPME with GC and HPLC, respectively. The sol–gel coating technology has led to the development of an extensive array of sol–gel sorbent coatings for SPME. In this article, sol–gel microextraction coatings are reviewed, with particular attention on their synthesis, characterization, and applications in conjunction with GC and HPLC analyses. In addition, the development of sol–gel‐coated stir bars, their inherent advantages, and applications are discussed. Next, the development and applications of sol–gel capillary microextraction (CME) in hyphenation with GC and HPLC is extensively reviewed. The newly emerging germania‐ and titania‐based sol–gel microextraction phases look promising, especially in terms of pH and hot solvent stability. Finally, sol–gel monolithic beds for CME are reviewed. Such monolithic beds are in a position to greatly improve the extracting capabilities and enhanced sensitivity in CME.