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Gas chromatographic analysis of methadone in urine samples after solid phase microextraction

โœ Scribed by Marcello Chiarotti; Remo Marsili


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
222 KB
Volume
6
Category
Article
ISSN
1040-7685

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โœฆ Synopsis


Abstract

The use of solid phase microextraction for quantitative analysis of methadone in urine is reported. The proposed procedure allows the extraction of methadone from a urine matrix, avoiding sample handling and saving evaporation of solvents and concentration steps. A fiber coated with polymethylsiloxane was employed for the extraction of methadone from urine and subsequently directly injected into the GUMS apparatus. Specific and reproducible results were obtained with high sensitivity.


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