Solid-phase microextraction SPME has been applied to the analysis of anorectic compounds from human urine. Urine samples from phendimetrazine and fenfluramine users, after the 1:1 dilution and addition of 400 ngrmL of Proadifen as an internal standard, have been directly sampled with SPME and analyz
Gas chromatographic analysis of methadone in urine samples after solid phase microextraction
โ Scribed by Marcello Chiarotti; Remo Marsili
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 222 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1040-7685
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โฆ Synopsis
Abstract
The use of solid phase microextraction for quantitative analysis of methadone in urine is reported. The proposed procedure allows the extraction of methadone from a urine matrix, avoiding sample handling and saving evaporation of solvents and concentration steps. A fiber coated with polymethylsiloxane was employed for the extraction of methadone from urine and subsequently directly injected into the GUMS apparatus. Specific and reproducible results were obtained with high sensitivity.
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