Software package for the management of sequencing projects using lacl transgenic animals

Mutational specificity: An efficient lab

Mutational specificity: An efficient laboratory protocol for the sequencing of large numbers of lacl mutants recovered from Big Blue® transgenic animals

✍ Heather L. Erfle; David F. Walsh; James Holcroft; Naheed Hague; Johan G. de Boer 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB 👁 2 views

Mutational spectra provide a powerful approach to investigate both the mutagenic potential and the mechanism of action of suspected mutagens and carcinogens. Recently, transgenic techniques have made it possible to generate mutational spectra in animals. Such a spectrum may consist of 5 0 to 200 mut