## Abstract The authors report, for the first time, sodium properties of human articular cartilage __in vivo__ using sodium multipleโquantumโfiltered methods with a surface coil. A flip angleโindependent, phaseโcycled pulse sequence was used to obtain tripleโquantumโfiltered spectra as a function o
Sodium multiple quantum spectroscopy of articular cartilage: Effects of mechanical compression
โ Scribed by Umamaheswar Duvvuri; Jonathan H. Kaufman; Saurabh D. Patel; Lizann Bolinger; J. Bruce Kneeland; John S. Leigh; Ravinder Reddy
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 511 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0740-3194
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โฆ Synopsis
The effects of mechanical compression on the multiple quantum coherences generated from sodium ions in articular cartilage were investigated. Cartilage samples obtained from bovine patellae were studied during compression at 0.7 MPa (100 psi) for 1 hour. The double quantum filtered spectra showed marked lineshape changes in the compressed samples. Compression did not seem to influence the lineshapes of the single quantum and triple quantum filtered spectra significantly. We found that the residual quadrupolar interaction was reduced in the compressed samples. Changes in the ordering of collagen fibers may be responsible for the observed effect.
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