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Sodium MRI of human articular cartilage in vivo

✍ Scribed by Dr. Ravinder Reddy; Erik K. Insko; Elizabeth A. Noyszewski; Rahul Dandora; John B. Kneeland; John S. Leigh

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
555 KB
Volume
39
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

Preliminary results from in vivo sodium MRI of human patellar articular cartilage are presented. Sodium images generated of an in vitro bovine patella clearly distinguish the region of proteoglycan depletion from the region of healthy cartilage. This provides the first evidence that sodium imaging may be used to detect changes due to osteoarthritis in vivo. The process of optimizing imaging time and signal‐to‐noise ratio, as well as potential implications in the detection of osteoar‐thritic change, are discussed.

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