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Sodium 2-ethylhexanoate: A mild acid scavenger useful in acylation of amines

✍ Scribed by John Fitt; Kapa Prasad; Oljan Repič; Thomas J. Blacklock


Book ID
104259883
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
109 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


A highly useful method for the acylation of amines with acid chlorides utilizing sodium 2-ethylhexanoate as the base is described. This procedure is superior to the Schotten-Baumann conditions whenever the product is water soluble.


📜 SIMILAR VOLUMES


ChemInform Abstract: Sodium 2-Ethylhexan
✍ J. FITT; K. PRASAD; O. REPIC; T. J. BLACKLOCK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB

Sodium 2-Ethylhexanoate: A Mild Acid Scavenger Useful in Acylation of Amines. -The acylation of amines with acid chlorides is efficiently achieved using 2-ethylhexanoate as base. Whenever the product is water-soluble, this procedure is superior to the Schotten-Baumann conditions.