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ChemInform Abstract: Sodium 2-Ethylhexanoate: A Mild Acid Scavenger Useful in Acylation of Amines.

✍ Scribed by J. FITT; K. PRASAD; O. REPIC; T. J. BLACKLOCK

Publisher: John Wiley and Sons
Year: 2010
Weight: 30 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199850068

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✦ Synopsis

Sodium 2-Ethylhexanoate: A Mild Acid Scavenger Useful in Acylation of Amines.

-The acylation of amines with acid chlorides is efficiently achieved using 2-ethylhexanoate as base. Whenever the product is water-soluble, this procedure is superior to the Schotten-Baumann conditions.

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