Endothelial cell dysfunction in response
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Nadia Jahroudi; Jana Kitney; Joel S. Greenberger; Robert Bowser
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Article
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1998
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John Wiley and Sons
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English
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Previous reports have shown that exposure of vascular endothelial and smooth muscle cells to exogenous amyloid beta (Aโค) peptide results in cell damage and toxicity via oxidative injury. In this study we demonstrate that overexpression of the amyloid precursor protein (APP) is toxic to bovine aortic