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SOCS3 negatively regulates LIF signaling in neural precursor cells

โœ Scribed by B. Emery; T.D. Merson; C. Snell; K.M. Young; M. Ernst; T.J. Kilpatrick

Book ID
116735423
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
378 KB
Volume
31
Category
Article
ISSN
1044-7431

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The peripheral nervous system consists of multiple neural lineages derived from the neural crest (NC). Pax-3 is expressed in the NC and when mutated in the splotch mouse (Sp) results in the loss of derivatives from this precursor cell population. We have investigated the role of Pax-3 in regulating