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SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymus

✍ Scribed by Zhan, Yifan; Davey, Gayle M; Graham, Kate L; Kiu, Hiu; Dudek, Nadine L; Kay, Thomas WH; Lew, Andrew M

Book ID
109864860
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
450 KB
Volume
87
Category
Article
ISSN
0818-9641

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## Abstract Regulatory T cells (Treg cells) have been well documented to have a crucial physiological role in preventing the development of autoimmune diseases and keeping self‐tolerance. Foxp3, a recently identified member of the forkhead transcription factors, serves as a master regulator for the