✦ LIBER ✦

SNPs in CAST are associated with Parkinson disease: A confirmation study

✍ Scribed by Andrew S. Allen; Glen A. Satten

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 139 KB
Volume: 9999B
Category: Article
ISSN: 1552-4841
DOI: 10.1002/ajmg.b.31061

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Glucocerebrosidase gene mutations are as

Glucocerebrosidase gene mutations are associated with Parkinson's disease in Russia

✍ Anton Emelyanov; Tatyana Boukina; Andrey Yakimovskii; Tatyana Usenko; Alesya Dro 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 341 KB 👁 1 views

FIG. 1. MRI showed symmetric (A) hypointensity signal on T1weighted imaging and (B) hyperintensity signal on T2-weighted imaging in bilateral substantia nigra on admission. A repeated MRI after 3 months showed resolution of the lesions on (C) T2-weighted imaging and (D) T1-weighted imaging.

Alpha-synuclein polymorphisms are associ

Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population

✍ Alex Rajput; Carles Vilariño-Güell; Michele L. Rajput; Owen A. Ross; Alexandra I 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB

## Abstract Alpha‐synuclein gene (__SNCA__) mutations cause familial Parkinsonism but the role of __SNCA__ variability in idiopathic Parkinson's disease (PD) remains incompletely defined. We report a study of __SNCA__ genetic variation in 452 idiopathic PD cases and 245 controls. __SNCA__ copy numb

LRRK2 G2019S mutations are associated wi

LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease

✍ Rachel Saunders-Pullman; Matthew J. Barrett; Kaili M. Stanley; Marta San Luciano 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB

## Abstract Leucine rich repeat kinase (__LRRK2__) G2019S mutations are presumed to cause PD through a toxic gain of function of the protein kinase. Small molecule kinase inhibitors have been developed for the treatment of certain cancers, and some antioncogenic agents such as sunitinib, may nonspe

GIGYF2 variants are not associated with

GIGYF2 variants are not associated with Parkinson's disease in Italy

✍ Monica Bonetti; Alessandro Ferraris; Martina Petracca; Anna Rita Bentivoglio; Br 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 47 KB 👁 1 views

Glucocerebrosidase gene mutations are as

Glucocerebrosidase gene mutations are associated with Parkinson's disease in southern Italy

✍ Elvira V. De Marco; Grazia Annesi; Patrizia Tarantino; Francesca E. Rocca; Giova 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

## Abstract Recent studies have reported an association between the glucocerebrosidase (__GBA__) gene and Parkinson's disease (PD). To elucidate the role of this gene in our population, we screened 395 PD patients and 483 controls from southern Italy for the N370S and the L444P mutations. We found

Comorbid conditions associated with Park

Comorbid conditions associated with Parkinson's disease: A population-based study

✍ Cynthia L. Leibson; Demetrius M. Maraganore; James H. Bower; Jeanine E. Ransom; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 1 views

## Abstract The burden of comorbidity in Parkinson's disease (PD) remains unclear. All Olmsted County, Minnesota, residents with incident PD in 1976–1995 (n = 197) plus one age‐ and sex‐matched non‐PD referent subject per case were followed for all clinical diagnoses from 5 years before through 15