SNPLims: a data management system for genome wide association studies
โ Scribed by Alessandro Orro; Guia Guffanti; Erika Salvi; Fabio Macciardi; Luciano Milanesi
- Book ID
- 115001636
- Publisher
- BioMed Central
- Year
- 2008
- Tongue
- English
- Weight
- 668 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1471-2105
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## Communicated by Pui-Yan Kwok Genome-wide association analysis appears to be a promising way to identify heritable susceptibility factors for complex human disorders. However, the feasibility of large-scale genotyping experiments is currently limited by an incomplete marker coverage of the genom
One of the most difficult issues to be solved in genome-wide association studies is to reduce the amount of genomic DNA required for genotyping. Currently available technologies require too large a quantity of genomic DNA to genotype with hundreds or thousands of singlenucleotide polymorphisms (SNPs