๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A high-throughput SNP typing system for genome-wide association studies

โœ Scribed by Y. Ohnishi; T. Tanaka; K. Ozaki; R. Yamada; H. Suzuki; Y. Nakamura


Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
501 KB
Volume
46
Category
Article
ISSN
1435-232X

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


A high-throughput SNP typing system for
โœ Y. Ohnishi; T. Tanaka; K. Ozaki; R. Yamada; H. Suzuki; Y. Nakamura ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 501 KB

One of the most difficult issues to be solved in genome-wide association studies is to reduce the amount of genomic DNA required for genotyping. Currently available technologies require too large a quantity of genomic DNA to genotype with hundreds or thousands of singlenucleotide polymorphisms (SNPs

A dynamic model for genome-wide associat
โœ Kiranmoy Das; Jiahan Li; Zhong Wang; Chunfa Tong; Guifang Fu; Yao Li; Meng Xu; K ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Springer ๐ŸŒ English โš– 756 KB
Kernel machine SNP-set analysis for cens
โœ Xinyi Lin; Tianxi Cai; Michael C. Wu; Qian Zhou; Geoffrey Liu; David C. Christia ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 442 KB ๐Ÿ‘ 2 views

In this article, we develop a powerful test for identifying single nucleotide polymorphism (SNP)-sets that are predictive of survival with data from genome-wide association studies. We first group typed SNPs into SNP-sets based on genomic features and then apply a score test to assess the overall ef

A novel bayesian graphical model for gen
โœ Yu Zhang ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 344 KB ๐Ÿ‘ 1 views

## Abstract Most disease association mapping algorithms are based on hypothesis testing procedures that test one variant at a time. Those methods lose power when the disease mutations are jointly tagged by multiple variants, or when geneโ€gene interaction exist. Nearby variants are also correlated,

Shrinkage estimation for robust and effi
โœ Sheng Luo; Bhramar Mukherjee; Jinbo Chen; Nilanjan Chatterjee ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 160 KB ๐Ÿ‘ 2 views

## Abstract Populationโ€based caseโ€control design has become one of the most popular approaches for conducting genomeโ€wide association scans for rare diseases like cancer. In this article, we propose a novel method for improving the power of the widely used singleโ€singleโ€nucleotide polymorphism (SNP

Avoiding the high Bonferroni penalty in
โœ Xiaoyi Gao; Lewis C. Becker; Diane M. Becker; Joshua D. Starmer; Michael A. Prov ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 104 KB ๐Ÿ‘ 2 views

## Abstract A major challenge in genomeโ€wide association studies (GWASs) is to derive the multiple testing threshold when hypothesis tests are conducted using a large number of single nucleotide polymorphisms. Permutation tests are considered the gold standard in multiple testing adjustment in gene