SNCA polymorphisms, smoking, and sporadic Parkinson’s disease in Japanese
✍ Scribed by Yoshihiro Miyake; Keiko Tanaka; Wakaba Fukushima; Chikako Kiyohara; Satoshi Sasaki; Yoshio Tsuboi; Tatsuo Yamada; Tomoko Oeda; Hiroyuki Shimada; Nobutoshi Kawamura; Nobutaka Sakae; Hidenao Fukuyama; Yoshio Hirota; Masaki Nagai
- Book ID
- 116821196
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 136 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1353-8020
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## Abstract Tyrosine hydroxylase (TH) is a theoretical candidate gene determining susceptibility to Parkinson's disease (PD), and an association between one allele of a polymorphism at the TH locus and sporadic PD has been reported. We investigated TH polymorphism in 44 patients with sporadic PD, 4
## Abstract We studied two genetic polymorphisms (240C/T and 480G/A) of the brain‐derived neurotrophic factor (BDNF) gene in Japanese patients with Alzheimer's disease (AD, n = 172), Parkinson's disease (PD, n = 327), and multiple system atrophy (MSA, n = 122), as well as controls (n = 275). The di