𝔖 Bobbio Scriptorium
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Snake venoms of the Bothrops genus activate complement by cleaving C1-inhibitor, C3 and C4

✍ Scribed by Giselle Pidde-Queiroz; Maria de Fátima Furtado; Carlos F. Filgueiras; Mônica Spadafora-Ferreira; Carmen W. van den Berg; Denise V. Tambourgi


Book ID
116757476
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
85 KB
Volume
46
Category
Article
ISSN
0161-5890

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Inhibition of complement components C3 a
✍ M. Andersson; A. Hanson; G. Englund; B. Dahlbäck 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 537 KB

The effect of cadralazine and its active metabolite CGP 22639 on the covalent binding reaction of C4 and C3 has been studied. Trypsin-Sepharose was used to activate radio-labelled C3 and C4 and binding of the radio-labelled protein to the trypsin-Sepharose was measured. Cadralazine inhibited 50% of