Twenty patients with squamous cell carcinoma of the head and neck (SCC H/N) were treated with Adriamycin (doxorubicin) at a dosage of 60 mg/m\* at 3-week intervals. No patient had received surgery, radiation, or chemotherapy before treatment with Adriamycin. Responses were observed in 44% of 18 eval
Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck : A population-based case-referent study in Sweden
✍ Scribed by Freddi Lewin; Staffan E. Norell; Hemming Johansson; Per Gustavsson; Johan Wennerberg; Anders Biörklund; Lars Erik Rutqvist
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 106 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
the years 1988-1990. A total of 605 cases were identified in the base, and 756 holm, Sweden.
controls were selected by stratified random sampling from population registries covering the base.
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We studied second primary cancer among 25,947 patients diagnosed with squamous cell carcinoma of the skin (SCC) in Sweden between 1958 and 1992. In total, 5,706 patients developed a second primary cancer at any site, compared with an expected number of 2,651 [standardized incidence ratio (SIR) ؍ 2
## Background: 5-fluorouracil (5-fu), as a single agent, produces a 15% response rate in advanced squamous cell carcinoma of the head and neck (scchn). n-phosphonacetyl-l-aspartate (pala) inhibits pyrimidine biosynthesis and increases incorporation of 5-fu metabolites into ribonucleic acid (rna). r