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SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy

โœ Scribed by See, K.; Yadav, P.; Giegerich, M.; Cheong, P. S.; Graf, M.; Vyas, H.; Lee, S. G. P.; Mathavan, S.; Fischer, U.; Sendtner, M.; Winkler, C.


Book ID
121361169
Publisher
Oxford University Press
Year
2013
Tongue
English
Weight
948 KB
Volume
23
Category
Article
ISSN
0964-6906

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Neurodevelopmental consequences of Smn d
โœ Hong Liu; Dina Shafey; Justin N. Moores; Rashmi Kothary ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 776 KB

## Abstract Deletions or mutations in __survival of motor neuron 1__ (__SMN1__) cause motor neuron loss and spinal muscular atrophy (SMA), a neuromuscular disorder, with the most severe type manifesting in utero. Whether SMA is a disease of defects in neurodevelopment and/or neuromaintenance remain