𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Combination of SMN Trans -Splicing and a Neurotrophic Factor Increases the Life Span and Body Mass in a Severe Model of Spinal Muscular Atrophy

✍ Scribed by Shababi, Monir; Glascock, Jacqueline; Lorson, Christian L.


Book ID
120062433
Publisher
Mary Ann Liebert
Year
2011
Tongue
English
Weight
436 KB
Volume
22
Category
Article
ISSN
1043-0342

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A rare SMN2 variant in a previously unre
✍ Myriam Vezain; Pascale Saugier-Veber; Elisa Goina; Renaud Touraine; VΓ©ronique Ma πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 405 KB

Spinal muscular atrophy (SMA) is a common neuromuscular disorder caused by homozygous inactivation of the SMN1 (Survival Motor Neuron 1) gene. The disease severity is mainly influenced by the copy number of SMN2, a nearly identical gene from which only low amounts of full-length mRNA are produced. T