𝔖 Bobbio Scriptorium
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Smiles rearrangements in the synthesis of hexachlorodibenzo-p-dioxins

✍ Scribed by Andrew S. Kende; Mark R. DeCamp


Book ID
104214927
Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
213 KB
Volume
16
Category
Article
ISSN
0040-4039

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✦ Synopsis


Chlorinated dibenzo-p-dioxlns pose a severe environmental hazard because of their extreme toxicity and persistence in the ecosystem.3 The compounds 1,2,3,7, 8,9-hexachlorodibenzo-p-dloxln 1 and 1,2,3,6,7,8-hexachlorodrbenzo-p-droxln 2 have been directly implicated in the death of millions of young chickens (chick edema).4 As part of our continuing program of synthesis, characterization, and biological evaluatron of toxic polychlorinated aromatics,5we undertook regrospecific syntheses of hexachlorodloxins 1 and 2. Since conventional techniques for


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