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SmI2-induced reductive cross-coupling of carbonyl compounds with (α,β-unsaturated esters

✍ Scribed by Kenji Otsubo; Junji Inanaga; Masaru Yamaguchi


Book ID
104219398
Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
135 KB
Volume
27
Category
Article
ISSN
0040-4039

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Treatment of sulfur-substituted aromatic lactams with carbonyl compounds in the presence of samarium(II) diiodide was found to undergo novel tandem desulfurization and reductive coupling reactions to generate a-hydroxyalkylated lactams in high yield. Stereochemistry of the coupling products was rese