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Small Molecule Tyrosine Kinase Inhibitors for the Treatment of Intestinal Inflammation

โœ Scribed by Sidhu, Maninder ;Alonso, Carmen ;Guleng, Bayasi ;Chang, SunYoung ;Chau, MyDoanh ;Ajami, Alfred M. ;Reinecker, Hans-Christian


Book ID
122294974
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
42 KB
Volume
140
Category
Article
ISSN
0016-5085

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Small molecule tyrosine kinase inhibitor
โœ Maninder Sidhu; Carmen Alonso Cotoner; Bayasi Guleng; Seiji Arihiro; Sunyoung Ch ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 774 KB

## Background: We developed a series of dendritic cell autoimmune modulators (DCAMs) based on small molecule Flt3 receptor tyrosine kinase inhibitors (TKIs) for the inhibition of intestinal inflammation and oral delivery. Methods: DCAMs were administered orally during and after induction of dextr