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Potent Small Molecule Inhibitors of Spleen Tyrosine Kinase (Syk).

โœ Scribed by Paul J. Cox; et al. et al.


Publisher
John Wiley and Sons
Year
2003
Weight
84 KB
Volume
34
Category
Article
ISSN
0931-7597

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Small molecule tyrosine kinase inhibitor
โœ Maninder Sidhu; Carmen Alonso Cotoner; Bayasi Guleng; Seiji Arihiro; Sunyoung Ch ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 774 KB

## Background: We developed a series of dendritic cell autoimmune modulators (DCAMs) based on small molecule Flt3 receptor tyrosine kinase inhibitors (TKIs) for the inhibition of intestinal inflammation and oral delivery. Methods: DCAMs were administered orally during and after induction of dextr